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Puerarin is the major bioactive ingredient isolated from the root of the Pueraria lobata (Willd.) Ohwi, which is well known as Gegen (Chinese name) in traditional Chinese medicine. As the most abundant secondary metabolite, puerarin was isolated from Gegen in the late 1950s. Since then, its pharmacological properties have been extensively investigated.
It is available in common foods and is used in alternative medicine. It has been widely used in the treatment of cardiovascular and cerebrovascular diseases, diabetes and diabetic complications, osteonecrosis, Parkinson's disease, Alzheimer's disease, endometriosis, and cancer.
The beneficial effects of puerarin on the various medicinal purposes may be due to its wide spectrum of pharmacological properties such as vasodilation, cardioprotection, neuroprotection, antioxidant, anticancer, antiinflammation, alleviating pain, promoting bone formation, inhibiting alcohol intake, and attenuating insulin resistance. However, the direct molecular mechanisms and targets remain unclear.
Goes Well With:
● Angelica dahurica (enhances absorption of Puerarin from Pueraria Lobata)
● Savlia Miltiorrhiza (Danshen) for anti-inflammatory purposes
The lone study on Kudzu root used a product containing 100mg of isoflavone equivalents, which appeared to be slightly effective for promoting cognition in postmenopausal women. It is unsure if this is near the optimal dosage or not.